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What is Mounjaro?
Mounjaro (tirzepatide) is a new medication licensed for weight loss in certain groups of people. The active ingredient (tirzepatide) was originally designed for use in the treatment of type 2 diabetes,¹ used to help manage blood sugar levels more effectively, but due to positive impact on peoples weight being seen it was approved for use in the treatment of obesity in 2023.Taken once a week through a simple injection, Mounjaro is now licensed for use as a weight loss medication.¹
Mounjaro (tirzepatide) is a new medication licensed for weight loss in certain groups of people. The active ingredient (tirzepatide) was originally designed for use in the treatment of type 2 diabetes,¹ used to help manage blood sugar levels more effectively, but due to positive impact on peoples weight being seen it was approved for use in the treatment of obesity in 2023.
Taken once a week through a simple injection, Mounjaro is now licensed for use as a weight loss medication.¹
How effective is Mounjaro?
Mounjaro has shown great results for weight loss. Clinical studies have shown that people using Mounjaro lose more weight compared to those on other weight loss medications.- Patients lost an average of 9.81 kg (about 21.6 lbs) compared to placebo, with even higher reductions at higher doses.2
- Weight loss increased with higher doses (5 mg, 10 mg, and 15 mg), demonstrating a clear dose-response relationship.2
- More participants achieved at least 5%, 10%, and 15% body weight reductions compared to those on placebo or other diabetes medications.2
Mounjaro has shown great results for weight loss. Clinical studies have shown that people using Mounjaro lose more weight compared to those on other weight loss medications.
- Patients lost an average of 9.81 kg (about 21.6 lbs) compared to placebo, with even higher reductions at higher doses.2
- Weight loss increased with higher doses (5 mg, 10 mg, and 15 mg), demonstrating a clear dose-response relationship.2
- More participants achieved at least 5%, 10%, and 15% body weight reductions compared to those on placebo or other diabetes medications.2
Overall mean baseline weight = 104.8kg
−3.1Placebo
−15.0Tirzepatide, 5mg
−19.5Tirzepatide, 10mg
−20.9Tirzepatide, 15mg
TRE
Percent change shown vs. baseline. Curves are a stylized visualization using representative sample points; final week-72 values match published outcomes (−3.1%, −15.0%, −19.5%, −20.9%).
Why does Mounjaro work?
Mounjaro has a unique approach to weight loss, as it targets two key pathways in the body. Here’s how it works:¹- Reduces appetite: Mounjaro helps to control hunger by affecting hormones that signal fullness, so you feel satisfied with less food.
- Boosts insulin sensitivity: It improves how your body uses insulin, which helps keep blood sugar levels stable and prevents energy crashes.
- Increases adiponectin levels: This hormone plays a role in regulating glucose levels and breaking down fatty acids, further supporting weight loss.
- Long-lasting effects: With a half-life of five days, Mounjaro stays active in your system, allowing for convenient once-weekly injections.
- Proven Results: Clinical studies have shown weight reductions of 16.5% to 22.4% over 72 weeks, even in patients without diabetes.
Mounjaro has a unique approach to weight loss, as it targets two key pathways in the body. Here’s how it works:¹
- Reduces appetite: Mounjaro helps to control hunger by affecting hormones that signal fullness, so you feel satisfied with less food.
- Boosts insulin sensitivity: It improves how your body uses insulin, which helps keep blood sugar levels stable and prevents energy crashes.
- Increases adiponectin levels: This hormone plays a role in regulating glucose levels and breaking down fatty acids, further supporting weight loss.
- Long-lasting effects: With a half-life of five days, Mounjaro stays active in your system, allowing for convenient once-weekly injections.
- Proven Results: Clinical studies have shown weight reductions of 16.5% to 22.4% over 72 weeks, even in patients without diabetes.
Mounjaro doses
2.5mg
Starting dose
Starting dose
5–7.5mg
Maintenance dose
5mg is the first maintenance dose, often prescribed after 4 weeks. 7.5mg is then available via a dose increase request
10–15mg
Higher maintenance
10mg and 15mg are the higher maintenance doses, achieved by titrating up by 2.5mg every 4 weeks
Who is eligible for Mounjaro?
Mounjaro is recommended for managing obesity as part of a comprehensive plan that includes a reduced-calorie diet and increased physical activity. To be eligible for Mounjaro, you must meet the following criteria:- An initial BMI of at least 30 kg/m².
- Or a BMI of 27 kg/m² to <30 kg/m² (overweight) in the presence of at least one weight-related comorbid condition.
Mounjaro is designed to support significant weight loss alongside lifestyle changes, helping to improve health outcomes for those at higher risk due to obesity. If you fit these criteria, then you may be eligible for treatment.Who should not take Mounjaro?
You shouldn't take Mounjaro if you:- Are pregnant or breastfeeding.
- Have a history of medullary thyroid cancer or MEN2 syndrome.
- Have severe gastrointestinal disease or pancreatitis.
- Are allergic to tirzepatide or any pen components.
Mounjaro is recommended for managing obesity as part of a comprehensive plan that includes a reduced-calorie diet and increased physical activity. To be eligible for Mounjaro, you must meet the following criteria:
- An initial BMI of at least 30 kg/m².
- Or a BMI of 27 kg/m² to <30 kg/m² (overweight) in the presence of at least one weight-related comorbid condition.
Mounjaro is designed to support significant weight loss alongside lifestyle changes, helping to improve health outcomes for those at higher risk due to obesity. If you fit these criteria, then you may be eligible for treatment.
Who should not take Mounjaro?
You shouldn't take Mounjaro if you:
- Are pregnant or breastfeeding.
- Have a history of medullary thyroid cancer or MEN2 syndrome.
- Have severe gastrointestinal disease or pancreatitis.
- Are allergic to tirzepatide or any pen components.
How to use Mounjaro?
Taking Mounjaro is simple and straightforward. It comes in a pre-filled injection pen that you take once a week. You can inject Mounjaro in the following areas:- Stomach: At least 2 inches away from your belly button.
- Thighs: Either thigh is suitable, just avoid the inner thigh.
- Upper arm: The back of the upper arm if someone else is administering the injection.
Make sure to rotate the injection site each week to prevent irritation. Avoid areas that are bruised, red, or sore. After use, simply dispose of the pen safely in a yellow sharps bin and you’re good to go.
Taking Mounjaro is simple and straightforward. It comes in a pre-filled injection pen that you take once a week. You can inject Mounjaro in the following areas:
- Stomach: At least 2 inches away from your belly button.
- Thighs: Either thigh is suitable, just avoid the inner thigh.
- Upper arm: The back of the upper arm if someone else is administering the injection.
Make sure to rotate the injection site each week to prevent irritation. Avoid areas that are bruised, red, or sore. After use, simply dispose of the pen safely in a yellow sharps bin and you’re good to go.
